The same antibiotics that improve and save so many human lives are also used to promote growth in farmed animals. In the US, the antibiotics used in industrial farming far exceed those given to humans; by weight, 73 percent of antibiotics, and 66 percent of antibiotics important to human medicine, are administered to farmed animals.1 In 2023, factory farms used such a large a volume of medically important antibiotics, like penicillins and tetracyclines, that they weighed a massive 13 million pounds—more than the combined weight of 95,000 adult human beings.2
The unnecessary “subtherapeutic” use of these life-saving drugs to increase industry profits contributes to the emergence of drug-resistant superbugs. And by propping up an agricultural system built upon crowding together sick, immunocompromised animals, the use of these drugs indirectly contributes to the emergence of novel viral pathogens like influenza and coronavirus that have the potential to cause human pandemics.
Part of the solution is obvious enough: we must alter farming methods so that they require fewer and ultimately no non-therapeutic drugs. As New York Times columnist Nicholas Kristof argued, we “need to curb the way modern agribusiness madly overuses antibiotics, leaving them ineffective for sick humans.”3
But it’s not necessarily a simple thing for a farmer to eliminate nontherapeutic antibiotic use. Each industry will need to address this issue differently and collectively to achieve lasting change. Consider the poultry industry, arguably where the most dangerous use of antibiotics takes place. For upwards of 99 percent of the chickens and turkeys raised for meat, their very genetics have been altered in synchronization with the development of specialized drug-laced feeds.
As poultry breeders abandoned traditional breeding techniques and engineered animals with the narrow aim of increasing growth and feed conversion rates, they also introduced a number of unwanted side effects, including weakened immune systems. The poultry industry knows about these problems, but instead of breeding healthier and slower-growing birds, its leaders have opted to “co-engineer” chickens and feed to make unhealthy animals as productive as possible. For decades, the poultry industry has used drugs in feed to compensate for immune deficiencies caused by their Frankenstein methods of breeding. The result is that to eliminate antibiotics on a large scale, the present methods of raising birds needs to be changed from bottom to top.
In fact, even if consumers buy antibiotic-free, pastured chickens, they have no choice but to support the misuse of antibiotics. How so? While buying chicken labeled as antibiotic-free or organic does ensure that the chicken you eat was not fed antibiotics, you can be quite certain that many of that bird’s parents, grandparents, and great-grandparents who were crossed to produce the bird were regularly given antibiotics.
The most pressing problem with the overuse of antimicrobials in poultry exists not on “grower” farms, which raise the birds we eat, but on the “breeder” farms. The chickens and turkeys we eat today are conceived on breeder farms, hatched in specialized hatcheries, and then move to separate grower farms. Most people don’t even know there are specialized breeder and grower farms, but this is a longstanding feature of the modern poultry industry. Historically this was advantageous because it allowed farmers to specialize in a particular area of production, but in today’s industry it is unavoidable because the hybrid chickens and turkeys people eat are “dead end” animals incapable of producing viable offspring.
Unless you buy a true heritage, standard-bred bird, even if you buy a chicken that had a relatively good life and was raised without drugs, that chicken’s parents and grandparents and great-grand parents almost certainly spent their lives confined in factory farm breeding facilities. In these facilities, the birds’ longer lives lead to an especially intense exposure to antibiotics and other antimicrobials. In contrast, true heritage chickens and turkeys have not been aggressively engineered in ways that compromise their immune systems.
Put simply, the public health risks posed by the use of antibiotics and antimicrobials in agriculture are symptoms of a larger problem: factory farming. The only sustainable solution is to change the way we eat and farm.
If you’re concerned about the dangers posed by anti-microbial use on today’s factory farms, perhaps it can serve as a motivation to reconsider what you eat. Moving meat from the center to the side of your plate, or off your plate altogether, is a powerful way you can make a statement against factory farming. If you are committed to eating meat, take steps to obtain it from a farmer you know and trust.4 Working together, we can change the way American eats and farms!
Want to understand more about antibiotics in animal production, including advice about speaking to local animal farmers? Check out Antibiotics 101.
U.S. Food and Drug Administration, “FDA Releases 2023 Antimicrobial for Food-Producing Animals Report,” U.S. Department of Health and Human Services, October 9, 2024; Rebecca Spirito, “FDA Report Shows Small Decline in Sales of Antibiotics for Food-Producing Animals,” CIDRAP, University of Minnesota, October 14, 2024; FoodSafety.com, “Sales of Medically Important Antibiotics for Use in Food-Producing Animals Decreased Slightly in 2023,” FoodSafety.com, October 15, 2024; all accessed September 15, 2025. Total weight of antibiotics sold for farmed animal production (~10.9 million kg) calculated from 6.1 million kg representing 56 percent of total farmed animal antibiotics; total weight of antibiotics used in human medicine (~4 million kg) estimated from national outpatient prescription and inpatient drug-dispensing data. See also David Wallinga et al., “A Review of the Effectiveness of Current US Policies on Antimicrobial Use in Meat and Poultry Production,” Current Environmental Health Reports 9, no. 2 (April 27 2022): 339–54.
Centers for Disease Control and Prevention, 2023 Summary Report on Antimicrobials Sold or Distributed for Use in Food-Producing Animals, PDF (Atlanta: U.S. Food and Drug Administration, 2024), accessed September 13, 2025.
Nicholas D. Kristof, “The Spread of Superbugs,” Opinion, The New York Times, March 6, 2010, (accessed March 9, 2010).
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